Name | 3,4-Dichlorophenylhydrazine hydrochloride |
Synonyms | 3,4-DICHLOROPHENYLHYDRAZINE HCL (3,4-dichlorophenyl)diazanium chloride 3,4-DICHLOROPHENYLHYDRAZINE HYDROCHLORIDE 3,4-Dichlorophenylhydrazine hydrochloride 3,4-Dichoropheynylhydrazine hydrochloride 1-(3,4-DICHLOROPHENYL)HYDRAZINE HYDROCHLORIDE (3,4-dichlorophenyl)hydrazine monohydrochloride |
CAS | 19763-90-7 |
EINECS | 243-278-0 |
InChI | InChI=1/C6H6Cl2N2.ClH/c7-5-2-1-4(10-9)3-6(5)8;/h1-3,10H,9H2;1H |
Molecular Formula | C6H7Cl3N2 |
Molar Mass | 213.49 |
Melting Point | 230°C (dec.)(lit.) |
Boling Point | 288.3°C at 760 mmHg |
Flash Point | 128.2°C |
Vapor Presure | 0.00236mmHg at 25°C |
Appearance | White powder |
BRN | 3703934 |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
MDL | MFCD00012937 |
Risk Codes | R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
UN IDs | 2811 |
WGK Germany | 3 |
HS Code | 29280000 |
Hazard Note | Harmful/Irritant |
Hazard Class | IRRITANT |
application | 3, 4-dichlorophenylhydrazine hydrochloride is a pharmaceutical intermediate that can be used to prepare biphenylpyridine. |
preparation method | compound 3,4-dichloroaniline (38.88g,0.2399mol) is dissolved in dichloroethane (30ml), then 12mol/L concentrated hydrochloric acid (70ml,0.84mol) is added, sodium nitrite (18.06g,0.261mol) is added, the reaction solution is stirred at 5 ℃ for 30min, and the clarified liquid is filtered out, drop to 140ml of sodium sulfite solution containing (90.71g,0.7197mol), react at 80 ℃ for about 3 hours, react to produce 3,4-dichlorophenylhydrazine, add about (60ml,0.72mol) concentrated hydrochloric acid for 1 hour, stir overnight at room temperature, filter to obtain 3,4-dichlorophenylhydrazine hydrochloride white solid 46.1g, yield: 90%. |